[ ] SIENA

Stimulation Initiative for European Neural Applications

Esprit Project 9811



Case Studies of Successful Applications



A New Method for Computer Assisted Prediciton of Lymphnode-Metastasis in Gastric Cancer

Company background

No information available

The problem

Preoperative staging especially of lymphnode-metastasis (LN-M) in patients with gastric cancer is very important for therapy decision. Neural nets, that are tested at present for industrial assignment such as robotics, language recognition, expert systems, etc., may offer new possibilities to this problem. The intention of this neural network application has been to evaluate if the accuracy of predicted frequency of lymphnode-metastasis is improvable.

Neural network application

For organization and training of the neural net were about 4000 datasettings at disposal. The simple neural net consisted of one layer of input neurons, representing values of predicting variables, one layer of output neurons, reflecting LN-M or no LN-M of one group of lymphnodes, and weighted junctions between these layers.. The weights of the junctions were learned by training the net with the given data.

Benefits

Neural networks are very tolerant related to inconsistence of data. The weights will be given regarding to discrepancy in data, missing values may be supplied. From this facts an opportunity for advancement of preoperative prediciton of lymphnode-metastasis may afford.

Generalization

The application of neural networks in cancer treatment is capable of simplifying therapy decisions and helps to avoid unnecessary surgery.

Contact person

Karin Droste - Dept. of Surgery, Technical University of Munich. Phone: + 49 89 4140-2147 Fax: +49 89 4140-4738